FGF23 Protein

Produktnummer ABIN7955973

Recombinant FGF23-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für FGF23 Protein (ABIN7955973)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by SDS-PAGE and HPLC analyses.

Produktdetails

Verwendungszweck: Recombinant Human Fibroblast Growth Factor 23

Sequenz: YPNASPLLGS SWGGLIHLYT ATARNSYHLQ IHKNGHVDGA PHQTIYSALM IRSEDAGFVV ITGVMSRRYL CMDFRGNIFG SHYFDPENCR FQHQTLENGY DVYHSPQYHF LVSLGRAKRA FLPGMNPPPY SQFLSRRNEI PLIHFNTPIP RRHTRSAEDD SERDPLNVLK PRARMTPAPA SCSQELPSAE DNSPMASDPL GVVRGGRVNT HAGGTGPEGC RPFAKFI

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 1 EU/ug of rHuFGF-23 as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2.0 x10³ IU/mg in the presence of 0.3 μg/ml of rMuKlotho and 10 μg/ml of heparin.

Anwendungsinformationen

Kommentare:

Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Haltbarkeit: 12 months

Antigendetails

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Andere Bezeichnung: Fibroblast Growth Factor 23

Molekulargewicht: 25.3 kDa

Gen-ID: 8074

UniProt: Q9GZV9

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion