FAS Protein (Soluble)
Kurzübersicht für FAS Protein (Soluble) (ABIN7937336)
Target
Alle FAS Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- Soluble
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Verwendungszweck
- Recombinant Human soluble Fas Receptor/TNFRSF6
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Sequenz
- RLSSKSVNAQ VTDINSKGLE LRKTVTTVET QNLEGLHHDG QFCHKPCPPG ERKARDCTVN GDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE INCTRTQNTK CRCKPNFFCN STVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 1 EU/ug of rHusFasR/TNFRSF6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 μg/ml in the presence of 2 ng/ml of rHuFas Ligand.
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Kommentare
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Approximately 17.6 kDa, a single non-glycosylated polypeptide chain containing 157 amino acids.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Haltbarkeit
- 12 months
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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Andere Bezeichnung
- Fas Receptor
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Molekulargewicht
- 17.6 kDa
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Gen-ID
- 355
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UniProt
- P25445
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Pathways
- p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Target
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