FLT3LG Protein
Kurzübersicht für FLT3LG Protein (ABIN7866467)
Target
Alle FLT3LG Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Human Flt-3 Ligand Protein
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Sequenz
- TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
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Spezifität
- Chromosomal location:19q13.3
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Produktmerkmale
- Length (aa):155
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Endotoxin-Niveau
- < 0.1 ng/μg of protein (< 1EU/μg)
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Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) (Active) protein (hFc Tag)
FLT3LG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) (Active) protein (His tag)FLT3LG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-184) protein (His tag,mFc Tag)FLT3LG Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-189) (Active) protein (hFc Tag)FLT3LG Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) protein (His tag)FLT3LG Spezies: Human Wirt: Hi-5 Cells Recombinant >90 % as determined by SDS-PAGE.
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-181) protein (His-IF2DI Tag)FLT3LG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 28-189) protein (His tag)FLT3LG Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 1-235) protein (GST tag)FLT3LG Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-188) protein (His tag)FLT3LG Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (Active) protein (His tag)GMP Grade FLT3LG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % WB Active
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Applikationshinweise
- Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 - 1 ng/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
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Andere Bezeichnung
- Flt-3 Ligand
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Hintergrund
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Synonyms: FLT3, FLK2, STK1, CD135, FLK-2
Description: Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
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Molekulargewicht
- 17.6 kDa
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Gen-ID
- 2323
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NCBI Accession
- NM_001459, NP_001450
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UniProt
- P49771
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Pathways
- RTK Signalweg
Target
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