IL-11 Protein

Produktnummer ABIN7849700

Dieses Recombinant IL-11-Protein wird in Yeast (Pichia pastoris) exprimiert.

Kurzübersicht für IL-11 Protein (ABIN7849700)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Yeast (Pichia pastoris)

Applikation: SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human IL-11 Protein

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: <0.01 EU/μg by LAL test

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: IL-11

Hintergrund:

Synonyms: IL11, AGIF, IL-11, interleukin 11

Description: Recombinant human IL-11 is produced by the yeast system, with the target gene encoding Gly23-Leu199 expressed.

Background: Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a protein that in humans is encoded by the IL11 gene.IL-11 is a cytokine that was first isolated in 1990 from bone marrow-derived fibrocyte-like stromal cells. It was initially thought to be important for hematopoiesis, notably for megakaryocyte maturation,but subsequently shown to be redundant for platelets, and for other blood cell types, in both mice and humans.It was developed as a recombinant protein (rhIL-11) as the drug substance oprelvekin.

UniProt: P20809

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion