Betacellulin Protein (BTC) (AA 32-118)

Produktnummer ABIN7827936

Dieses Recombinant Betacellulin-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Betacellulin Protein (BTC) (AA 32-118) (ABIN7827936)

Target: Betacellulin (BTC)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 32-118

Verwendungszweck: Human Betacellulin Protein

Sequenz: Asp32-Gln118

Produktmerkmale: Recombinant Human Betacellulin Protein is expressed from E.coli without tag.It contains Asp32-Gln118.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 0.1 EU per μg by the LAL method.

Biological Activity Comment: Human Betacellulin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50-for this effect is 0.10-1.50 ng/ml (QC Test).,The purity of Human Betacellulin is greater than 95% as determined by SEC-HPLC.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Betacellulin (BTC)

Andere Bezeichnung: Betacellulin

Hintergrund: Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family.

Molekulargewicht: 9.76 kDa. The protein migrates to 14-18 kDa based on Bis-Tris PAGE result.

UniProt: P35070

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung