Poliovirus Receptor Protein (PVR) (AA 1-343) (His tag)

Produktnummer ABIN7669450

Dieses Recombinant Poliovirus Receptor-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Poliovirus Receptor Protein (PVR) (AA 1-343) (His tag) (ABIN7669450)

Target: Poliovirus Receptor (PVR)

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-343

Aufreinigungstag / Konjugat: Dieses Poliovirus Receptor Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD155/PVR/NECL5 protein (His tag)

Sequenz: Met1-Asn343

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: CD155,PVR,NECL5

Hintergrund: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.,CD155,NECL-5,Nectin-Like Protein 5,PVR,PVS,Poliovirus Receptor

Molekulargewicht:

calculated_mw: 37.6 kDa

observed_mw: 60 kDa

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom