IFN omega (Active) protein (His tag)

Produktnummer ABIN7668916

Dieses Recombinant IFN omega-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für IFN omega (Active) protein (His tag) (ABIN7668916)

Target: IFN omega

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Cell Culture (CC)

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Recombinant Human IFN omega protein(His Tag)

Sequenz: Cys 24-Ser 195

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 0.1 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measure by its ability to induce cytotoxicity in TF-1 cells. The ED₅₀ for this effect is <0.02 ng/mL. The specific activity of recombinant human IFN omega is approximately >5 x10⁷ IU/ mg.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IFN omega

Hintergrund: Interferon omega-1 is also known as Interferon alpha-II-1and IFNW1. It is a Secreted protein that in humans is encoded by the IFNW1 gene. IFNW1 belongs to the alpha/beta interferon family. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. IFNW1 is a recently discovered protein structurally related to IFN-alpha and -beta. It has been shown that IFN-omega 1 similar to that of other human class I IFNs, potent antiviral activity was also observed on cells of bovine and ovine but not of equine or murine origin.,IFN alpha II-1,IFNW1

Molekulargewicht:

calculated_mw: 20.9 kDa

observed_mw: 20 kDa

UniProt: P05000