IFN omega (Active) Protein

Produktnummer ABIN2468552

Recombinant IFN omega-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IFN omega (Active) Protein (ABIN2468552)

Target: IFN omega

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: < 98 % by SDS-PAGE gel and HPLC analyses.

Produktdetails

Sequenz: MCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS

Produktmerkmale: The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is < 0.01 ng/mL, corresponding to a specific activity of > 1 x 10⁶ units/mg.

Endotoxin-Niveau: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing IFN-omega recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IFN-omega is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: IFN omega

Andere Bezeichnung: IFN-omega

Hintergrund: IFN-omega is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-a, IFN-B, and IFN-w, signal through IFNAR-1/IFNAR-2 receptor complex, and exert anti-viral and anti-proliferative activities. IFN-omega exhibits about 75 % sequence homology with IFN-a, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-omega is a 19.9 kDa protein consisting of 172 amino acid residues.

Gen-ID: 3467

NCBI Accession: NP_002168

OMIM: 4504605

UniProt: P05000