Hepcidin Protein (AA 59-83) (His-TRX)

Produktnummer ABIN7668892

Dieses Recombinant Hepcidin-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Hepcidin Protein (AA 59-83) (His-TRX) (ABIN7668892)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 59-83

Aufreinigungstag / Konjugat: Dieses Hepcidin Protein ist gelabelt mit His-TRX.

Verwendungszweck: Recombinant Mouse Hepcidin/Hepc protein (TRX,His tag)

Sequenz: Asp59-Thr83

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: Hepcidin,Hepc

Hintergrund: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.,HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1,Hepcidin

Molekulargewicht:

calculated_mw: 22.6 kDa

observed_mw: 25 kDa

UniProt: Q9EQ21

Pathways: Hormone Activity, Transition Metal Ion Homeostasis