Galectin 3 Protein (LGALS3) (His tag)

Produktnummer ABIN7668810

Recombinant Galectin 3-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Galectin 3 Protein (LGALS3) (His tag) (ABIN7668810)

Target: Galectin 3 (LGALS3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Immunogen (Imm)

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Galectin 3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Galectin-3 Protein(His Tag)

Sequenz: 2Ala-250Iie

Aufreinigung: SDS-PAGE analysis of Human Galectin-3 proteins, 2μg/lane of Recombinant Human Galectin-3 proteins was resolved with SDS-PAGE under reducing conditions, showing bands at 32 KD

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3

Hintergrund: MAC,Galactose-specific lectin,Galactoside-Binding Soluble,Galectin,Lectin L,GAL,CBP,LGALS3,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2,Galactoside-Binding Soluble 3,Lectin,Galectin-3,Gal-3,L-31,35 kDa lectin,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,galactose binding,galactoside binding soluble 3,Galactoside-binding protein,galectin 3,Galectin 3 internal gene,Galectin3,GBP,IgE binding protein,included,L 31,L 34,L-34 galactoside-binding lectin,Lectin,Galactoside-Binding Soluble 3,LEG3,MAC 2 antigen,Mac-2,Macrophage galactose-specific lectin,MGC105387,P35,soluble 3,Galectin-3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. Galectin-3 has an important role in tumor progression throμgh inhibition of apoptosis. Galectin-3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of Galectin-3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with Galectin-3 include Follicular Adenoma and Papillary Carcinoma.

Molekulargewicht:

Calculated MW: 27.4 kDa

Observed MW: 32 kDa

Gen-ID: 3958

UniProt: P17931

Pathways: RTK Signalweg