Neuregulin 1 Protein (NRG1) (AA 177-241)

Produktnummer ABIN7607518

Produktdetails

Target: Neuregulin 1 (NRG1)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 177-241

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB), SDS-PAGE (SDS), Immunogen (Imm), ELISA, Activity Assay (AcA)

Verwendungszweck: Recombinant Human NRG1/Neuregulin-1 Protein, No tag (Active)

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: <1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured in a serum-free cell proliferation assay using human breast cancer cells (MCF-7). The ED50 for this effect is 20-100 ng/mL.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Haltbarkeit: 12 months

Antigendetails

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: Glial growth factor (NRG1 Produkte)

Hintergrund: Glial growth factor, Neu differentiation factor, SMDF, Breast cancer cell differentiation factor p45, Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity, ARIA, GGF, HRGA, Pro-NRG1, HGL, HRG, NDF, NRG1, Sensory and motor neuron-derived factor, Heregulin

UniProt: Q02297

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation