AGAP3 Protein (AA 1-910) (His tag)

Produktnummer ABIN7564760

Produktdetails

Target: AGAP3 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 3 (AGAP3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-910

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses AGAP3 Protein ist gelabelt mit His tag.

Verwendungszweck: Made-to-order recombinant Agap3 Protein expressed in mammalian cells.

Sequenz: MNFQAGGGQS PQQQQSLAAP GGGGAAAQQL VCGGQFGGAG PGAGGGGPSQ QLAGGPPQQF ALSNSAAIRA EIQRFESVHP NIYAIYDLIE RIEDLALQNQ IREHVISIED SFVNSQEWTL SRSVPELKVG IVGNLSSGKS ALVHRYLTGT YVQEESPEGG RFKKEIVVDG QSYLLLIRDE GGPPELQFAA WVDAVVFVFS LEDEISFQTV YNYFLRLCSF RNASEVPMVL VGTQDAISAA NPRVIDDSRA RKLSTDLKRC TYYETCATYG LNVERVFQDV AQKVVALRKK QQLAIGPCKS LPNSPSHSAV SAASIPAVHI NQATNGGSSA FSDYSSSVPS TPSISQRELR IETIAASSTP TPIRKQSKRR SNIFTSRKGA DLDREKKAAE CRVDSIGSGR AIPIKQGILL KRSGKSLNKE WKKKYVTLCD NGLLTYHPSL HDYMQNIHGK EIDLLRTTVK VPGKRLPRAT PTTAPGTSPR ANGLAMERSN TQLGGATGAP HSASSTSLHS ERPHSSAWAG SRPGPEGLHQ RSCSVSSTDQ WSEAAALPAS MQHPASGPAE SLSSSPKLEP PPSPHSNRKK HRGKKSTGTP RPDGPSSAAE EAEESFEFVV VSLTGQTWHF EASTAEEREL WVQSVQAQIL ASLQGCRSAK DKTRLGNQNT ALAVQAVRTV RGNSLCIDCE APNPDWASLN LGALMCIECS GIHRHLGAHL SRVRSLDLDD WPPELLAVMT AMGNALANSV WEGALDGYSK PGPEACREEK ERWIRAKYEQ KLFLAPLPSS DVPLGQQLLR AVVEDDLRLL VMLLAHGSKE EVNETYGDGD GRTALHLSSA MANVVFTQLL IWYGVDVRSR DARGLTPLAY ARRAGSQECA DILIQHGCPG EGCGLAPTPN REPANGTNPS AELHRSPSIL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: AGAP3 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 3 (AGAP3))

Andere Bezeichnung: Agap3 (AGAP3 Produkte)

Hintergrund: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1),FUNCTION: GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway. {ECO:0000269|PubMed:16461359, ECO:0000305}.

Molekulargewicht: 98.0 kDa

UniProt: Q8VHH5

AlphaFold: Q8VHH5

Pathways: Protein targeting to Nucleus