GRAMD4 Protein (AA 1-633) (His tag)

Produktnummer ABIN7559224

Produktdetails

Target: GRAMD4 (GRAM Domain Containing 4 (GRAMD4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-633

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GRAMD4 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Gramd4 Protein expressed in mammalian cells.

Sequenz: MGIASHSAFR ERESSPTGAS LDASPRPWDK GLSGREPPRH VQVRPRSAVL NMLRRLDRIR FRGHKREDLL DLAESPNASD TECGDEIPLK TPRPSPRDSE ELRDPAGPGT LIMAAGVQDF NRTEFDRLNE IKGHLEIALL EKHFLQEELR KLREETNSEM LRQELDRERQ RRIELEQKMQ EVLKARSEEQ PAQPQQPPKG QSQASNGTGT ERRSQGLASR VQKWFYERFG EYIEDFRFQP EENTVETEEP LSARRLTENM RRLKRGAKPV TNFVKNLSAL SDWYSIYTSA IAFTVYMNAV WHGWAIPMFL FLAILRLSLN YLIARGWRIQ WSIVPEVSEA VEPAKEDLTV SEKFQLVLDV AQKAQNLFGK MADILEKIKN LFMWVQPETT QKLYVALWAA FLASCFFPYR LVGLAVGLYA GIKFFLIDFI FKRCPRLRAK YDTPYIIWRS LPTDPQLKER AGATVSRRLQ TASSRSYVSS APAGLSKDED AGRFHSTKKG NFHEIFNLTE NERPLAVCEN GWRCCLINRD RKMPTDYIRN GVLYVTENYL CFESSKSGSS KRNKVIKLMD ITDIQKYKVL SVLPGSGMGI AVSTPSTQKP LVFGAMVHRD EAFETIFSQY VKITSAAASG GDS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: GRAMD4 (GRAM Domain Containing 4 (GRAMD4))

Andere Bezeichnung: Gramd4 (GRAMD4 Produkte)

Hintergrund: GRAM domain-containing protein 4 (Death-inducing protein),FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (By similarity). Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (PubMed:25917084). {ECO:0000250|UniProtKB:Q6IC98, ECO:0000269|PubMed:25917084}.

Molekulargewicht: 72.3 kDa

UniProt: Q8CB44

AlphaFold: Q8CB44