BCL3 Protein (AA 1-448) (His tag)

Produktnummer ABIN7556427

Produktdetails

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-448

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BCL3 Protein ist gelabelt mit His tag.

Verwendungszweck: Custom-made recombinant Bcl3 Protein expressed in mammalian cells.

Sequenz: MPRCPAGAMD EGPVDLRTRP KGTPGAALPL RKRPLRPASP EPATTRSPAG PLDALRSGCD VPVVPGPPHC VARPEALYYQ GPLMPIYSTP TMAPHFPLLN LPTHPYSMIC PMEHPLSADI AMATRVDEDG DTPLHIAVVQ NNIAAVYRIL SLFKLGSREV DVHNNLRQTP LHLAVITTLP DMVRLLVTAG ASPMALDRHG QTAIHLACEH RSPSCLQALL DSATSGSVDL EVRNYEGLTA LHVAVNTGCQ EAVLLLLERG ADIDAVDIKS GRSPLIHAVE NNSLNMVQLL LLHGANVNAQ MYSGSSALHS ASGRGLLPLV RTLVRSGADS GLKNCHNDTP LMVARSRRVI DILRGKASRA ASGSQPEPSP DQSATNSPES SSRLSSNGLQ SSPSSSPSLS PPKDAPGFPA TPQNFFLPTT STPAFLPFPG VLRGPGRPVP PSPAPGSS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: Bcl3 (BCL3 Produkte)

Hintergrund: B-cell lymphoma 3 protein homolog (BCL-3),FUNCTION: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity). In the nucleus, acts as a transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. {ECO:0000250, ECO:0000269|PubMed:16713561}.

Molekulargewicht: 47.2 kDa

UniProt: Q9Z2F6

AlphaFold: Q9Z2F6

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus