ARRDC4 Protein (AA 1-415) (His tag)

Produktnummer ABIN7556160

Produktdetails

Target: ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-415

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARRDC4 Protein ist gelabelt mit His tag.

Verwendungszweck: Made-to-order recombinant Arrdc4 Protein expressed in mammalian cells.

Sequenz: MGGEAGADGP RGRVKSLGLV FEDESKGCYS SGETVAGHVL LEAAEPVALR GLRLEAQGRA TSAWGPSAGA RVCIGGGSPA ASSEVEYLNL RLSLLEAPAG EGVTLLQPGK HEFPFRFQLP SEPLATSFTG KYGSIQYCVR AVLERPQVPD QSVRRELQVV SHVDVNTPPL LTPMLKTQEK MVGCWLFTSG PVSLSVKIER KGYCNGEAIP IYAEIENCSS RLVVPKAAIF QTQTYLASGK TKTVRHMVAN VRGNHIGSGS TDTWNGKMLK IPPVTPSILD CCIIRVDYSL AVYIHIPGAK RLMLELPLVI GTIPYSGFGR RNSSVASQFS MDMCWLALAL PEQPEAPPNY ADVVSEEEFS RHVPPYPQPS DCDGEACYSM FACIQEFRFQ PPPLYSEVDP HPGDAQETQP VSFIL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: ARRDC4 (Arrestin Domain Containing 4 (ARRDC4))

Andere Bezeichnung: Arrdc4 (ARRDC4 Produkte)

Hintergrund: Arrestin domain-containing protein 4,FUNCTION: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:27462458). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (By similarity). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). May play a role in glucose uptake (By similarity). Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65 (By similarity). {ECO:0000250|UniProtKB:Q8NCT1, ECO:0000269|PubMed:27462458}.

Molekulargewicht: 45.0 kDa

UniProt: A0A0B4J1F4

AlphaFold: A0A0B4J1F4