IL-4 Protein

Produktnummer ABIN7539338

Dieses Recombinant IL-4-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für IL-4 Protein (ABIN7539338)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % by SDS-PAGE and Coomassie stain

Produktdetails

Verwendungszweck: IL-4

Sequenz: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S

Spezifität: Chromosomal location:11 B1.3, 11 29.0 cM

Kreuzreaktivität: Human, Blutegel, Maus, Schwein, Ratte, Forelle

Produktmerkmale: Length (aa):120

Endotoxin-Niveau: < 0.1 ng/μg of protein (<1EU/μg)

Anwendungsinformationen

Applikationshinweise: The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 10^5 units/mg.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Antigendetails

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: IL-4

Hintergrund: Il4, Il-4, BSF-1,Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.

Molekulargewicht: 13.5 kDa

Gen-ID: 16189

NCBI Accession: NM_021283, NP_067258

UniProt: P07750

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation