FGF10 Protein

Produktnummer ABIN7539320

Dieses Recombinant FGF10-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für FGF10 Protein (ABIN7539320)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by SDS-PAGE

Produktdetails

Verwendungszweck: FGF-10

Sequenz: MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

Spezifität: Chromosomal location:5p13-p12

Kreuzreaktivität: Huhn, Human, Maus

Produktmerkmale: Length (aa):170

Anwendungsinformationen

Applikationshinweise: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/mL, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: The lyophilized FGF-10 should be reconstituted in water to a concentration not lower than 50 μg/mL. For long term storage we would recommend to add at least 0.1 % human or bovine serum albumin.

Buffer: 0.5X PBS

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Lyophilized samples are stable for more than six months at -20°C to -70°C.

Antigendetails

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF-10

Hintergrund: FGF10, KGF2,Fibroblast Growth Factor-10 (FGF-10) is a heparin binding growth factor which stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is most related to KGF/FGF-7 and is expressed during development and preferentially in adult lungs. Human FGF-10 is a 19.3 kDa protein containing 170 amino acid residues.

Molekulargewicht: 19.3 kDa

Gen-ID: 2255

NCBI Accession: NM_004465, NP_004456

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus