CD70 Protein (Fc Tag)

Produktnummer ABIN7538175

Dieses Recombinant CD70-Protein wird in Mammalian Cells exprimiert.

Kurzübersicht für CD70 Protein (Fc Tag) (ABIN7538175)

Target: CD70 (CD70 Molecule (CD70))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Mammalian Cells

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD70 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant mouse CD70 protein with N-terminal human Fc tag

Spezifität: HFc (Glu99-Ala330) Mouse CD70 (Ser45-Pro195)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: Predicted to enable cytokine activity and protease binding activity. Predicted to be involved in several processes, including B cell proliferation, T cell mediated immunity, and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage, hip, and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 Molecule). [provided by Alliance of Genome Resources, Apr 2022]

Molekulargewicht: predicted molecular mass of 42.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mCD70 is 35-70 kDa due to glycosylation.

UniProt: O55237

Pathways: Cancer Immune Checkpoints