PDGF-BB Homodimer (Active) Protein

Produktnummer ABIN7520387

Dieses Recombinant -Protein wird in Yeast (Pichia pastoris) exprimiert.

Kurzübersicht für PDGF-BB Homodimer (Active) Protein (ABIN7520387)

Target: PDGF-BB Homodimer

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Yeast (Pichia pastoris)

Produktdetails

Verwendungszweck: Recombinant Human PDGF-BB Protein

Sequenz: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT

Spezifität: Ser82-Thr190

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1EU/μg

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized PDGF-BB at 2 μg/mL (100 μL/well) can bind Human PDGFRB with a linear range of 0.1-104.7 ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Konzentration: 0.3 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: PDGF-BB Homodimer

Andere Bezeichnung: PDGF-BB

Hintergrund:

Description: Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.

Name: SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2,PDGF subunit B,PDGF-BB,PDGFB

Gen-ID: 5155

UniProt: P01127