CXCL3 Protein

Produktnummer ABIN7535397

Dieses Recombinant CXCL3-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CXCL3 Protein (ABIN7535397)

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 85 % by SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human CXCL3/GRO-gamma/MIP2-beta Protein

Sequenz: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

Spezifität: Ala35-Asn107

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Andere Bezeichnung: CXCL3/GRO-gamma/MIP2-beta

Hintergrund:

Description: CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

Name: CXCL3,CINC-2b,GRO3,GROg,MIP-2b,MIP2B,SCYB3

Gen-ID: 2921

UniProt: P19876

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagie