DKK1 Protein (AA 32-142, N-Term) (mFc Tag)

Produktnummer ABIN7504308

Dieses Recombinant DKK1-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für DKK1 Protein (AA 32-142, N-Term) (mFc Tag) (ABIN7504308)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 32-142, N-Term

Aufreinigungstag / Konjugat: Dieses DKK1 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Human DKK1 N terminal Domain Protein

Sequenz: Thr32-Asp142

Produktmerkmale: Recombinant Human DKK1 N terminal Domain Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Thr32-Asp142.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human DKK1 N terminal Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human DKK1 N terminal Domain is greater than 95% as determined by SEC-HPLC.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1

Hintergrund: Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes.

Molekulargewicht: 37.35 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.

UniProt: O94907

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation