STXBP3 Protein

Produktnummer ABIN7482130

Recombinant STXBP3-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für STXBP3 Protein (ABIN7482130)

Target: STXBP3 (Syntaxin Binding Protein 3 (STXBP3))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Proliferation Assay (ProA)

Reinheit: ≥98 % (HPLC)

Produktdetails

Verwendungszweck: Recombinant human Persephin protein

Sequenz: ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG

Spezifität: Toxin target: GFRα4 and RET receptor complex

Biological Activity Comment: Persephin promotes the survival of mesencephalic, dopaminergic and motor neurons1,2. The receptor for Persephin is a multicomponent complex composed of RET tyrosine kinase and the glycosyl-phosphatidylinositol (GPI)-anchored co-receptor GFR α1-α43,4.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. Reconstitute in sterile, high-purity water at a concentration of at least 0.1 mg/mL. For long-term storage, aliquot the solution into small, single-use vials and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. For storage of dilute working solutions, we recommend adding a carrier protein (e.g., 0.1 % BSA) to your buffer to prevent material loss due to protein adsorption. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

Buffer: Lyophilized from PBS.

Handhabung: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

Lagerung: -20 °C

Informationen zur Lagerung: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Antigendetails

Target: STXBP3 (Syntaxin Binding Protein 3 (STXBP3))

Andere Bezeichnung: PSP

Hintergrund: A recombinant human neurotrophic factor that promotes the survival of dopaminergic and motor neurons, primarily via the GFRα4 and RET receptor complex

Molekulargewicht: 20.6 kDa (dimer)

UniProt: O60542

Pathways: Hormone Transport