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PDGF-BB Homodimer Protein

Dieses Recombinant -Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN7455626

Kurzübersicht für PDGF-BB Homodimer Protein (ABIN7455626)

Target

PDGF-BB Homodimer

Protein-Typ

Recombinant

Spezies

  • 8
  • 5
  • 3
Human

Quelle

  • 10
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

Greater than 98 % as determined by reducing SDS-PAGE.
  • Verwendungszweck

    Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.

    Produktmerkmale

    Extracellular Domain Protein

    Aufreinigung

    Affinity purification
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    PDGF-BB Homodimer

    Andere Bezeichnung

    PDGF-BB

    Hintergrund

    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

    Molekulargewicht

    12.42 KDa

    UniProt

    P01127
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