CD79a Protein (His tag)

Produktnummer ABIN7448058

Produktdetails

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Protein-Typ: Recombinant

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD79a Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus CD79A Protein, His Tag

Sequenz: Leu 33 - Arg 142

Produktmerkmale: Cynomolgus CD79A, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Arg 142 (Accession # XP_045235481.1).

Reinheit: 90,00 %

Endotoxin-Niveau: 1.0 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.4 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: RT

Informationen zur Lagerung: RT

Antigendetails

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: CD79A (CD79A Produkte)

Synonyme: CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein

Hintergrund: Synonyms:CD79A, CD79a, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated p,Description:B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain(CD79a), also known as CD79α, IgM-α, Ig-α and mb-1, which is a signaling component of the preB cell receptor (preBCR). Covalently linked CD79a and CD79b heterodimer constitutes the B cell antigen receptor (BCR) with membrane immunoglobulin (mIg) in a non-covalent association. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR), leading to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.

Molekulargewicht: 14.4 kDa

NCBI Accession: XP_045235481

Pathways: BCR Signaling