PLA2G1B Protein (AA 23-146) (hFc Tag)

Produktnummer ABIN7275463

Dieses Recombinant PLA2G1B-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für PLA2G1B Protein (AA 23-146) (hFc Tag) (ABIN7275463)

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 23-146

Aufreinigungstag / Konjugat: Dieses PLA2G1B Protein ist gelabelt mit hFc Tag.

Verwendungszweck: Mouse PLA2G1B Protein

Sequenz: Ala23-Cys146

Produktmerkmale: Recombinant Mouse PLA2G1B Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala23-Cys146.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse PLA2G1B on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse PLA2G1B is greater than 95% as determined by SEC-HPLC.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Andere Bezeichnung: PLA2G1B

Hintergrund: Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA).

Molekulargewicht: 40.9 kDa. Due to glycosylation, the protein migrates to 48-50 kDa based on Bis-Tris PAGE result.

UniProt: Q9Z0Y2

Pathways: Inositol Metabolic Process, VEGF Signaling