NOG Protein (AA 28-232)
Kurzübersicht für NOG Protein (AA 28-232) (ABIN7275358)
Target
Alle NOG Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 28-232
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Verwendungszweck
- Human Noggin Protein
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Sequenz
- Gln28-Cys232
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Produktmerkmale
- Recombinant Human Noggin Protein is expressed from CHO without tag.It contains Gln28-Cys232.
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Sterilität
- 0.22 μm filtered
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Endotoxin-Niveau
- Less than 0.05 EU per μg by the LAL method.
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Noggin (NOG) (AA 20-232) (Active) protein
NOG Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) (AA 28-232) (Active) proteinNOG Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) protein (His tag)NOG Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (His tag)NOG Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Noggin (NOG) (AA 28-232) protein (GST tag)NOG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Noggin (NOG) protein (Fc Tag)NOG Spezies: Human Wirt: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (Fc Tag)NOG Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- NOG (Noggin (NOG))
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Andere Bezeichnung
- Noggin
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Hintergrund
- Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β-catenin, EGFR, ERK and Akt.
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Molekulargewicht
- 23.05 kDa. Due to glycosylation, the protein migrates to 30-36 kDa based on Tris-Bis PAGE result.
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UniProt
- Q13253
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Pathways
- Stem Cell Maintenance, Tube Formation
Target
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