Klotho beta Protein (KLB) (AA 53-994) (His tag)

Produktnummer ABIN7275093

Dieses Recombinant Klotho beta-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Klotho beta Protein (KLB) (AA 53-994) (His tag) (ABIN7275093)

Target: Klotho beta (KLB)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 53-994

Aufreinigungstag / Konjugat: Dieses Klotho beta Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse Beta Klotho Protein

Sequenz: Phe53-Pro994

Produktmerkmale: Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Klotho beta (KLB)

Andere Bezeichnung: Beta Klotho

Hintergrund: Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.

Molekulargewicht: 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.

UniProt: Q99N32-1

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Growth Factor Binding