IL-9 Protein (AA 19-144) (His tag)

Produktnummer ABIN7274984

Recombinant IL-9-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für IL-9 Protein (AA 19-144) (His tag) (ABIN7274984)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 19-144

Aufreinigungstag / Konjugat: Dieses IL-9 Protein ist gelabelt mit His tag.

Verwendungszweck: Human IL-9 Protein

Sequenz: Gln19-Ile144

Produktmerkmale: Recombinant Human IL-9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln19-Ile144.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human IL-9, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-IL-9 Anitibody, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Andere Bezeichnung: IL-9

Hintergrund: IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.

Molekulargewicht: 15.3 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

UniProt: P15248

Pathways: JAK-STAT Signalweg