IL-7 Protein (AA 26-177)
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- Target Alle IL-7 (IL7) Proteine anzeigen
- IL-7 (IL7) (Interleukin 7 (IL7))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-177
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Verwendungszweck
- Human IL-7 Protein
- Sequenz
- Asp26-His177
- Produktmerkmale
- Recombinant Human IL-7 Protein is expressed from E.coli without tag.It contains Asp26-His177.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). The affinity constant of 7.15 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL-7 (IL7) (Interleukin 7 (IL7))
- Andere Bezeichnung
- IL-7 (IL7 Produkte)
- Hintergrund
- Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor.
- Molekulargewicht
- 17.5 kDa same as Tris-Bis PAGE result.
- UniProt
- P13232
- Pathways
- JAK-STAT Signalweg
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