Hemopexin Protein (HPX) (AA 24-460) (His tag)

Produktnummer ABIN7274828

Recombinant Hemopexin-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für Hemopexin Protein (HPX) (AA 24-460) (His tag) (ABIN7274828)

Target: Hemopexin (HPX)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 24-460

Aufreinigungstag / Konjugat: Dieses Hemopexin Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse HPX Protein

Sequenz: Ser24-Gln460

Produktmerkmale: Recombinant Mouse HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Gln460.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 150 mM NaCl ( pH 6.0).

Buffer: Lyophilized from 0.22μm filtered solution in 50 mM MES, 150 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Hemopexin (HPX)

Andere Bezeichnung: HPX

Hintergrund: Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.

Molekulargewicht: 50 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

UniProt: Q91X72

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response