GM-CSF Protein (AA 18-144)
Kurzübersicht für GM-CSF Protein (AA 18-144) (ABIN7274780)
Target
Alle GM-CSF (CSF2) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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    - 
                                            Proteineigenschaft
- AA 18-144
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                                            Verwendungszweck
- Human GM-CSF Protein
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                                            Sequenz
- Ala18-Glu144
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                                            Produktmerkmale
- Recombinant Human GM-CSF Protein is expressed from E.coli without tag.It contains Ala18-Glu144.
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                                            Sterilität
- 0.22 μm filtered
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                                            Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
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                                            Biological Activity Comment
- Immobilized Human GM-CSF at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human GM-CSF R alpha, hFc Tag with the EC50 of 18.5ng/ml determined by ELISA. The affinity constant of 0.79nM as determined in SPR assay (Biacore T200). See testing image for detail.
 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Lyophilized
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                                            Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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                                            Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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    - GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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                                            Andere Bezeichnung
- GM-CSF
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                                            Hintergrund
- Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim.
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                                            Molekulargewicht
- 14.6 kDa same as Tris-Bis PAGE result.
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                                            UniProt
- P04141
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                                            Pathways
- JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin
 Target
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