FOLR1 Protein (AA 25-232) (His tag)

Produktnummer ABIN7274669

Recombinant FOLR1-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für FOLR1 Protein (AA 25-232) (His tag) (ABIN7274669)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 25-232

Aufreinigungstag / Konjugat: Dieses FOLR1 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse FOLR1 Protein

Sequenz: Thr25-Ser232

Produktmerkmale: Recombinant Mouse FOLR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr25-Ser232.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Andere Bezeichnung: FOLR1

Hintergrund: Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH .

Molekulargewicht: 25.36 kDa. Due to glycosylation, the protein migrates to 33-43 kDa based on Tris-Bis PAGE result.

UniProt: P35846

Pathways: Dicarboxylic Acid Transport