CD226 Protein (CD226) (AA 19-247) (His-Avi Tag,Biotin)
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- Target Alle CD226 Proteine anzeigen
- CD226
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 19-247
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD226 Protein ist gelabelt mit His-Avi Tag,Biotin.
- Verwendungszweck
- Biotinylated Human DNAM-1/CD226 Protein
- Sequenz
- Glu19-Asn247
- Produktmerkmale
- Recombinant Biotinylated Human DNAM-1/CD226 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu19--Asn247.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 264nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product CD226 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD226
- Andere Bezeichnung
- DNAM-1 (CD226 Produkte)
- Hintergrund
- DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
- Molekulargewicht
- 28.9 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q15762
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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