CD226 Protein (CD226) (AA 19-247) (His-Avi Tag)
Kurzübersicht für CD226 Protein (CD226) (AA 19-247) (His-Avi Tag) (ABIN7274455)
Target
Alle CD226 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 19-247
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Aufreinigungstag / Konjugat
- Dieses CD226 Protein ist gelabelt mit His-Avi Tag.
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Verwendungszweck
- Human DNAM-1/CD226 Protein
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Sequenz
- Glu19-Asn247
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Produktmerkmale
- Recombinant Human DNAM-1/CD226 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu19-Asn247.
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Sterilität
- 0.22 μm filtered
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Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- The affinity constant of 0.22μM as determined in SPR assay (Biacore T200). See testing image for detail.
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CD226 (CD226) (AA 19-247) protein (Fc Tag)
CD226 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-252) protein (His tag)CD226 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag,Biotin)CD226 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-247) protein (mFc-His Tag)CD226 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) protein (His tag)CD226 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
CD226 (CD226) proteinCD226 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD226 (CD226) (Active) protein (His tag)CD226 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD226 (CD226) (Active) protein (Fc Tag)CD226 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- CD226
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Andere Bezeichnung
- DNAM-1
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Hintergrund
- DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
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Molekulargewicht
- 28.9 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q15762
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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