PEA15 Protein
Kurzübersicht für PEA15 Protein (ABIN7318180)
Target
Alle PEA15 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
-
-
Verwendungszweck
- Recombinant Human Astrocytic Phosphoprotein PEA-15/PEA15 Protein
-
Sequenz
- Met 1-Ala130
-
Produktmerkmale
- Recombinant Human Phosphoprotein Enriched in Astrocytes of 15 kDa is produced by our E.coli expression system and the target gene encoding Met1-Ala130 is expressed.
-
Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 12.620,45 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 20.480,57 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 1-130) protein (His tag)
custom-made PEA15 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 1-130) protein (His tag)custom-made PEA15 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 1-130) protein (GST tag)PEA15 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
phosphoprotein Enriched in Astrocytes 15 (PEA15) protein (Myc-DYKDDDDK Tag)PEA15 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Kommentare
-
12-16 kDa
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Please refer to the printed manual for detailed information.
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
-
Lagerung
- 4 °C,-20 °C,-80 °C
-
Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
-
Andere Bezeichnung
- PEA15
-
Hintergrund
-
Background: Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm. In addition, PEA15 inhibits both TNFRSF6 and TNFRSF1A mediated CASP8 activity and apoptosis. At present, PEA15 expression is also a significant prognostic marker in ovarian cancer.
Synonym: Astrocytic Phosphoprotein PEA-15, 15 kDa Phosphoprotein Enriched in Astrocytes, Phosphoprotein Enriched in Diabetes, PED, PEA15
-
Molekulargewicht
- 15.3 kDa
-
UniProt
- Q15121
Target
-
