Apolipoprotein C-II Protein (APOC2) (His tag)
Kurzübersicht für Apolipoprotein C-II Protein (APOC2) (His tag) (ABIN7318171)
Target
Alle Apolipoprotein C-II (APOC2) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Apolipoprotein C-II Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)
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Sequenz
- Met 1-Glu82
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Produktmerkmale
- Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Kommentare
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14 kDa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mMPB,150 mM NaCL,30 % glycerol, pH 7.2.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Apolipoprotein C-II (APOC2)
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Andere Bezeichnung
- Apolipoprotein C-II
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Hintergrund
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Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
Synonym: Apolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2
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Molekulargewicht
- 10.0 kDa
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UniProt
- P02655
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Pathways
- Lipid Metabolism
Target
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