Vitronectin Protein (VTN) (His tag)

Produktnummer ABIN7319175

Recombinant Vitronectin-Protein exprimiert in Human Cells.

Kurzübersicht für Vitronectin Protein (VTN) (His tag) (ABIN7319175)

Target: Vitronectin (VTN)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Vitronectin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Vitronectin/VTN Protein (His Tag)(Active)

Sequenz: Asp20-Leu478

Produktmerkmale: Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Asp20-Leu478 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by the ability of the immobilized protein to support the adhesion of Jurkat cells.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Vitronectin (VTN)

Andere Bezeichnung: Vitronectin/VTN

Hintergrund:

Background: Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM, Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site, plus cleavage sites for elastase, thrombin, and plasmin.

Synonym: Vitronectin, VN, S-Protein, Serum-Spreading Factor, V75, VTN

Molekulargewicht: 53.4 kDa

UniProt: P04004

Pathways: Autophagie, Smooth Muscle Cell Migration