USP14 Protein (His tag)
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- Target Alle USP14 Proteine anzeigen
- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses USP14 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human USP14 Protein (His Tag)
- Sequenz
- Asp91-Gln494
- Produktmerkmale
- Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase 14 is produced by our E.coli expression system and the target gene encoding Asp91-Gln494 is expressed with a 6His tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product USP14 Protein
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Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) protein (GST tag)
USP14 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin Specific Peptidase 14 (USP14) proteinUSP14 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494), (full length) protein (His tag)USP14 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Ubiquitin Specific Peptidase 14 (USP14) (Transcript Variant 2) protein (His tag)USP14 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 20 % Glycerol, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
- Andere Bezeichnung
- USP14 (USP14 Produkte)
- Hintergrund
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Background: Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 located in the cytoplasm is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. In addition, USP14 is indispensable for synaptic development and function at neuromuscular junctions, required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.
Synonym: Ubiquitin Carboxyl-Terminal Hydrolase 14, Deubiquitinating Enzyme 14, Ubiquitin Thioesterase 14, Ubiquitin-Specific-Processing Protease 14, USP14, TGT
- Molekulargewicht
- 48.5 kDa
- UniProt
- P54578
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