Thrombomodulin Protein (THBD) (His tag)
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- Target Alle Thrombomodulin (THBD) Proteine anzeigen
- Thrombomodulin (THBD)
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses Thrombomodulin Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse Thrombomodulin/THBD Protein (His Tag)
- Sequenz
- Leu17-Ser517
- Produktmerkmale
- Recombinant Mouse Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Leu17-Ser517 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Thrombomodulin (THBD) protein (His tag)
THBD Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Thrombomodulin (THBD) (AA 19-515) protein (His tag)Crystallography grade THBD Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Thrombomodulin (THBD) (AA 17-517) protein (His tag)Crystallography grade THBD Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Thrombomodulin (THBD) (AA 19-575) protein (rho-1D4 tag)Crystallography grade THBD Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Thrombomodulin (THBD) (AA 17-577) protein (rho-1D4 tag)Crystallography grade THBD Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Thrombomodulin (THBD)
- Andere Bezeichnung
- Thrombomodulin/THBD (THBD Produkte)
- Synonyme
- AHUS6 Protein, BDCA3 Protein, CD141 Protein, THPH12 Protein, THRM Protein, TM Protein, AI385582 Protein, THBD Protein, HAST Protein, HAST3 Protein, M-PST Protein, ST1A3/ST1A4 Protein, ST1A5 Protein, STM Protein, TL-PST Protein, thrombomodulin Protein, sulfotransferase family 1A member 3 Protein, THBD Protein, Thbd Protein, SULT1A3 Protein
- Hintergrund
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Background: Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). In addition, THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer.
Synonym: Thrombomodulin, TM, Fetomodulin, CD141, BDCA-3, Thbd
- Molekulargewicht
- 54.6 kDa
- UniProt
- P15306
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