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Thrombomodulin Protein (THBD) (His tag)

THBD Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Produktnummer ABIN7198229
  • Target Alle Thrombomodulin (THBD) Proteine anzeigen
    Thrombomodulin (THBD)
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Ratte
    Quelle
    • 12
    • 4
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Thrombomodulin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Rat Thrombomodulin Protein (His Tag)
    Sequenz
    Met1-Ser517
    Produktmerkmale
    A DNA sequence encoding the rat THBD (O35370) (Met1-Ser517) was expressed with a polyhistidine tag at the C-terminus.
    Reinheit
    > 90 % as determined by SDS-PAGE
    Endotoxin-Niveau
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product THBD Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Thrombomodulin (THBD)
    Andere Bezeichnung
    Thrombomodulin (THBD Produkte)
    Synonyme
    AHUS6 Protein, BDCA3 Protein, CD141 Protein, THPH12 Protein, THRM Protein, TM Protein, AI385582 Protein, THBD Protein, HAST Protein, HAST3 Protein, M-PST Protein, ST1A3/ST1A4 Protein, ST1A5 Protein, STM Protein, TL-PST Protein, thrombomodulin Protein, sulfotransferase family 1A member 3 Protein, THBD Protein, Thbd Protein, SULT1A3 Protein
    Hintergrund

    Background: Thrombomodulin, also known as THBD(CD141), is an integral membrane protein which reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome.

    Synonym: THBD

    Molekulargewicht
    55.2 kDa
    UniProt
    O35370
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