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Syndecan 1 Protein (SDC1) (His tag)

This anti-Syndecan 1 antibody (ABIN7320206) is a HEK-293 Cells antibody detecting Syndecan 1 in . Suitable for Mouse.
Produktnummer ABIN7320206

Kurzübersicht für Syndecan 1 Protein (SDC1) (His tag) (ABIN7320206)

Target

Alle Syndecan 1 (SDC1) Proteine anzeigen
Syndecan 1 (SDC1)

Protein-Typ

Recombinant

Spezies

  • 24
  • 8
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Maus

Quelle

  • 18
  • 13
  • 4
  • 3
  • 1
  • 1
HEK-293 Cells

Reinheit

> 80 % as determined by SDS-PAGE
  • Aufreinigungstag / Konjugat

    Dieses Syndecan 1 Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Mouse Syndecan-1/SDC1 Protein (His Tag)

    Sequenz

    Met 1-Glu 252

    Produktmerkmale

    A DNA sequence encoding the extracellular domain of mouse SDC1 (NP_035649.1) (Met 1-Glu 252) was expressed, with a C-terminal polyhistidine tag.

    Endotoxin-Niveau

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Syndecan 1 (SDC1)

    Andere Bezeichnung

    Syndecan-1/SDC1

    Hintergrund

    Background: Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.

    Synonym: AA408134,AA409076,CD138,Sstn,syn-1,Synd,Synd1

    Molekulargewicht

    26 kDa

    NCBI Accession

    NP_035649

    Pathways

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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