SPHK1 Protein (His-GST)
Kurzübersicht für SPHK1 Protein (His-GST) (ABIN7317044)
Target
Alle SPHK1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
-
-
Aufreinigungstag / Konjugat
- Dieses SPHK1 Protein ist gelabelt mit His-GST.
-
Verwendungszweck
- Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag)
-
Sequenz
- Met 1-Leu 384
-
Produktmerkmale
- A DNA sequence encoding the human SPHK1 (Q9NYA1-1)(Met1-Leu384) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus.
-
Sterilität
- 0.2 μm filtered
-
Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 11.737,02 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 15.754,29 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (His tag)
custom-made SPHK1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-382) protein (His tag)custom-made SPHK1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (GST tag)SPHK1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Sphingosine Kinase 1 (SPHK1) (Active) proteinSPHK1 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10 % glycerol, pH 8.0
-
Konservierungsmittel
- Dithiothreitol (DTT)
-
Vorsichtsmaßnahmen
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
Haltbarkeit
- 6 months
-
-
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
-
Andere Bezeichnung
- SPHK1/Sphingosine Kinase 1
-
Hintergrund
- SPHK,SPHK1,SPK,SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
-
Molekulargewicht
-
Calculated MW: 70.3 kDa
Observed MW: 64 kDa
-
Gen-ID
- 8877
-
UniProt
- Q9NYA1
-
Pathways
- VEGF Signaling
Target
-
