PSPH Protein (His tag)

Produktnummer ABIN7318903

Dieses Recombinant PSPH-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für PSPH Protein (His tag) (ABIN7318903)

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PSPH Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PSPH Protein (His Tag)

Sequenz: Met 1-Glu225

Produktmerkmale: Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Andere Bezeichnung: PSPH

Hintergrund:

Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

Synonym: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH

Molekulargewicht: 26.1 kDa

UniProt: P78330

Pathways: Warburg Effekt