PMVK Protein (His tag)

Produktnummer ABIN7318901

Dieses Recombinant PMVK-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für PMVK Protein (His tag) (ABIN7318901)

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PMVK Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Phosphomevalonate Kinase/PMVK Protein (His Tag)

Sequenz: Met 1-Leu192

Produktmerkmale: Recombinant Human Phosphomevalonate Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu192 is expressed with a 6His tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Andere Bezeichnung: Phosphomevalonate Kinase/PMVK

Hintergrund:

Background: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney, it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.

Synonym: Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI

Molekulargewicht: 24.2 kDa

UniProt: Q15126