PMVK Protein (AA 1-192) (His tag)

Produktnummer ABIN1097355

Produktdetails

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-192

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PMVK Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Phosphomevalonate Kinase/PMVK (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MAPLGGAPRL VLLFSGKRKS GKDFVTEALQ SRLGADVCAV LRLSGPLKEQ YAQEHGLNFQ RLLDTSTYKE AFRKDMIRWG EEKRQADPGF FCRKIVEGIS QPIWLVSDTR RVSDIQWFRE AYGAVTQTVR VVALEQSRQQ RGWVFTPGVD DAESECGLDN FGDFDWVIEN HGVEQRLEEQ LENLIEFIRS RL

Produktmerkmale: Recombinant Human Phosphomevalonate Kinase/PMVK is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Leu192) of Human PMVK fused with a His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Andere Bezeichnung: Phosphomevalonate Kinase/PMVK (PMVK Produkte)

Synonyme: MPK_Bm Protein, F5M6.9 Protein, F5M6_9 Protein, zgc:162701 Protein, HUMPMKI Protein, PMK Protein, PMKA Protein, PMKASE Protein, 1110011E12Rik Protein, 2900002L22Rik Protein, AV001327 Protein, phosphomevalonate kinase Protein, GHMP kinase family protein Protein, PMVK Protein, Mpk Protein, AT1G31910 Protein, CpipJ_CPIJ015413 Protein, Bm1_05275 Protein, pmvk Protein, LOAG_11811 Protein, Tsp_06629 Protein, LOC100282968 Protein, Pmvk Protein

Sub Type: Fusionprotein

Hintergrund: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney, it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
Alternative Names: Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI

Molekulargewicht: 24.2 kDa

UniProt: Q15126