P-Cadherin Protein (CDH3) (Fc Tag)

Produktnummer ABIN7320475

Dieses Recombinant P-Cadherin-Protein wird in Human Cells exprimiert.

Kurzübersicht für P-Cadherin Protein (CDH3) (Fc Tag) (ABIN7320475)

Target: P-Cadherin (CDH3)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Reinheit: > 90 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses P-Cadherin Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Mouse Cadherin-3/CDH3 Protein (Fc Tag)

Sequenz: Glu100-Gly647

Produktmerkmale: Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: P-Cadherin (CDH3)

Andere Bezeichnung: Cadherin-3/CDH3

Hintergrund:

Background: Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

Synonym: Cadherin-3, Placental cadherin, P-cadherin, Cdh3

Molekulargewicht: 87.5 kDa

UniProt: P10287