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Neurotrophin 3 Protein (NTF3)

NTF3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7318822
  • Target Alle Neurotrophin 3 (NTF3) Proteine anzeigen
    Neurotrophin 3 (NTF3)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 11
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 18
    • 7
    • 2
    • 2
    Escherichia coli (E. coli)
    Verwendungszweck
    Recombinant Human Neurotrophin-3/NTF3 Protein (Active)
    Sequenz
    Tyr139-Thr 257
    Produktmerkmale
    Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human NT-3 at 10ug/ml(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .
    Top Product
    Discover our top product NTF3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Neurotrophin 3 (NTF3)
    Andere Bezeichnung
    Neurotrophin-3/NTF3 (NTF3 Produkte)
    Synonyme
    HDNF Protein, NGF-2 Protein, NGF2 Protein, NT3 Protein, NT-3 Protein, wu:fl98d04 Protein, hdnf Protein, ngf-2 Protein, ngf2 Protein, nt-3 Protein, nt3 Protein, NTF3 Protein, AI316846 Protein, AI835689 Protein, Nt3 Protein, Ntf-3 Protein, neurotrophin 3 Protein, neurotrophin 3 S homeolog Protein, neurotrophin 3 L homeolog Protein, NTF3 Protein, ntf3 Protein, ntf3.S Protein, Ntf3 Protein, ntf3.L Protein
    Hintergrund

    Background: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

    Synonym: Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3

    Molekulargewicht
    13.6 kDa
    UniProt
    P20783
    Pathways
    RTK Signalweg, Neurotrophin Signalübertragung
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