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NFASC Protein (His tag)

Dieses Recombinant NFASC-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN7317169

Kurzübersicht für NFASC Protein (His tag) (ABIN7317169)

Target

Alle NFASC Proteine anzeigen
NFASC (Neurofascin (NFASC))

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 3
  • 2
  • 1
HEK-293 Cells

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses NFASC Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Human NFASC/Neurofascin protein (His Tag)

    Sequenz

    Met 1-Gln939

    Produktmerkmale

    A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    NFASC (Neurofascin (NFASC))

    Andere Bezeichnung

    NFASC/Neurofascin

    Hintergrund

    Background: NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.

    Synonym: NF,NRCAML

    Molekulargewicht

    104.4 kDa

    Pathways

    Cell-Cell Junction Organization
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