MAX Protein (His-GST)

Produktnummer ABIN7317333

Dieses Recombinant MAX-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für MAX Protein (His-GST) (ABIN7317333)

Target: MAX (MYC Associated Factor X (MAX))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses MAX Protein ist gelabelt mit His-GST.

Verwendungszweck: Recombinant Human MAX Protein (His &GST Tag)

Sequenz: Met 1-Ser160

Produktmerkmale: A DNA sequence encoding the human MAX (NP_002373) (Met1-Ser160) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MAX (MYC Associated Factor X (MAX))

Andere Bezeichnung: MAX

Hintergrund: BHLHD4,Class D Basic Helix-Loop-Helix Protein 4,MAX,Myc-Associated Factor X,Protein Max,bHLHd4,MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to MAX family. It is highly expressed in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. MYC associated factor X may also repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Multiple alternatively spliced transcript variants have been described for MYC associated factor X gene but the full-length nature for some of them is unknown.

Molekulargewicht:

Calculated MW: 46.1 kDa

Observed MW: 73 kDa

Gen-ID: 4149

NCBI Accession: NP_002373

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases