MINPP1 Protein (His tag)

Produktnummer ABIN7318790

Produktdetails

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses MINPP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human MINPP1 Protein (His Tag)

Sequenz: Ser31-Leu487

Produktmerkmale: Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Andere Bezeichnung: MINPP1 (MINPP1 Produkte)

Synonyme: HIPER1 Protein, MINPP2 Protein, MIPP Protein, AA408516 Protein, minpp1 Protein, zgc:56080 Protein, zgc:76991 Protein, zgc:153026 Protein, multiple inositol-polyphosphate phosphatase 1 Protein, multiple inositol polyphosphate histidine phosphatase 1 Protein, multiple inositol-polyphosphate phosphatase 1b Protein, multiple inositol-polyphosphate phosphatase 1a Protein, MINPP1 Protein, Minpp1 Protein, minpp1b Protein, minpp1a Protein

Hintergrund:

Background: Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).

Synonym: Multiple Inositol Polyphosphate Phosphatase 1, 2,3-Bisphosphoglycerate 3-Phosphatase, 2,3-BPG Phosphatase, Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase, Ins(1,3,4,5)P(4) 3-Phosphatase, MINPP1, MIPP

Molekulargewicht: 53.1 kDa

UniProt: Q9UNW1